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Tazemetostat
Tazemetostat Current developer: Epizyme, Inc., Cambridge, MA 02139. EPZ-6438 (Tazemetostat) CAS: 1403254-99-8 Chemical Formula: C34H44N4O4 Exact Mass: 572.33626...
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Evofosfamide
Evofosfamide, HAP-302 , TH-302 Evofosfamide Names IUPAC name (1-Methyl-2-nitro-1H-imidazol-5-yl)methyl N,N’-bis(2-bromoethyl)phosphorodiamidate Other names TH-302; HAP-302 Identifiers CAS Registry...
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ZSTK 474
4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine ZSTK474; 475110-96-4;...
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BEZ 235 (NVP-BEZ235), Dactolisib
BEZ235 (NVP-BEZ235)Dactolisib 4-[2,3-dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4, 5-c]quinolin-1-yl]-α,α-dimethyl-benzeneacetonitrile...
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Honokiol, from magnolia bark, shuts down cancer cells in lab
Magnolia virginiana Honokiol, from magnolia bark, shuts down cancer cells in lab Compound in magnolia may combat head and neck cancers Honokiol, from magnolia bark, shuts down cancer cells in lab...
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AXITINIB
Axitinib (AG013736; trade name Inlyta) is a small molecule tyrosine kinase inhibitor developed by Pfizer. It has been shown to significantly inhibit growth of breast cancer in animal (xenograft)...
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ASLAN Pharmaceuticals Gains Orphan Designation for Rare Cancer Drug ASLAN001...
(R)-N4-[3-Chloro-4-(thiazol-2-ylmethoxy)-phenyl]-N6-(4-methyl-4,5-dihydro-oxazol-2-yl)-quinazoline-4,6-diamine ASLAN001 , Varlitinib C22H19ClN6O2S Molecular Weight: 466.94 Elemental Analysis: C,...
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Pevonedistat
Millennium Pharmaceuticals, Inc. INNOVATOR Millennium Pharmaceuticals, Inc., a subsidiary of Takeda Pharmaceutical Company Limited, MLN4924, MLN 4924-003, TAK-924 905579-51-3 BASE 1160295-21-5 HcL A...
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Vintafolide
Vintafolide, EC-145 , MK-8109 mw 1917.041, cas 742092-03-1, mf C86 H109 N21 O26 S2...
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Chi-Med Says Fruquintinib Successful in Lung Cancer Trial
Fruquintinib Phase 3…cancer Hutchison Medipharma Enterprises Limited Hutchison MediPharma for the treatment of locally advanced or metastatic colorectal cancer C21H19N3O5 Exact Mass: 393.1325 cas...
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Beijing Shenogen Granted Fast Track Status for Novel Cancer Drug, Icaritin
Icaritin; 118525-40-9; AC1NSXIV; UNII-UFE666UELY; 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one...
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CEP 18770, Delanzomib
CEP-18770, Delanzomib cas 847499-27-8 Chemical Formula: C21H28BN3O5 Exact Mass: 413.21220, UNII-6IF28942WO; CT-47098 NPH 007098 NPH007098...
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AMG-319
AMG-319 N-((1S)-1-(7-fluoro-2-(2-pyridinyl)-3-quinolinyl)ethyl)-9H-purin-6-amine, WO2008118468 (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine CAS 1608125-21-8 Chemical...
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FDA approves new oral therapy to treat ALK-positive lung cancer
FDA approves new oral therapy to treat ALK-positive lung cancer 12/11/2015 01:03 PM EST The U.S. Food and Drug Administration today approved Alecensa (alectinib) to treat people with advanced...
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VAL-083
VAL-083 (1R,2S)-1-((R)-oxiran-2-yl)-2-((S)-oxiran-2-yl)ethane-1,2-diol Galactitol, 1,2:5,6-dianhydro- 1,2:5,6-Dianhydrodulcitol 1,2:5,6-Dianhydrogalactitol 1,2:5,6-Diepoxydulcitol...
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Talazoparib, BMN 673
Talazoparib, BMN-673, MDV-3800 (2S,3S)-methyl-7-fluoro-2-(4-fluorophenyl)-3-(1-methyl-1H-1,2,4-triazol-5-yl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate...
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ODM-201
ODM 201, BAY 1841788; ODM-201 N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide CAS 1297538-32-9 Chemical Formula: C19H19ClN6O2 Exact...
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Trioxacarcin A
Trioxacarcin A, DC-45A CAS No. 81552-36-5 Molecular FormulaC42H52O20 Average mass876.850 Da...
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EGF 816 , Nazartinib
EGF 816, Nazartinib EGF-816; EGFRmut-TKI EGF816 Novartis Ag innovator (R,E)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide...
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罗西替尼 роцилетиниб روسيليتينيب Rociletinib, CO-1686. Third generation covalent...
Rociletinib (CO-1686) AVL-301,CNX-419 Celgene (Originator) , Clovis Oncology N-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5- (trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide...
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